Lesion-induced DNA weak structural changes detected by pulsed EPR spectroscopy combined with site-directed spin labelling
نویسندگان
چکیده
منابع مشابه
Lesion-induced DNA weak structural changes detected by pulsed EPR spectroscopy combined with site-directed spin labelling
Double electron-electron resonance (DEER) was applied to determine nanometre spin-spin distances on DNA duplexes that contain selected structural alterations. The present approach to evaluate the structural features of DNA damages is thus related to the interspin distance changes, as well as to the flexibility of the overall structure deduced from the distance distribution. A set of site-direct...
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ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 2009
ISSN: 1362-4962,0305-1048
DOI: 10.1093/nar/gkp165